Molecular Evolution and Phylogenetics by Masatoshi Nei and Sudhir Kumar 2000 Paperback

$ 22.18

Item Length: 7 in Dewey Decimal: 572.838 brand: Oxford University Press, Incorporated Item Weight: 28.2 Oz ISBN-13: 9780195135855 Author: Masatoshi Nei, Sudhir Kumar Publication Name: Molecular Evolution and Phylogenetics Item Height: 0.9 in Dewey Edition: 21 Illustrated: Yes Number of Pages: 352 Pages Synopsis: This book presents the statistical methods that are useful in the study of molecular evolution and illustrates how to use them in actual data analysis. Molecular evolution has been developing at a great pace over the past decade or so, driven by the huge increase in genetic sequence data from many organisms, the improvement of high-speed microcomputers, and the development of several new methods for phylogenetic analysis. This book for graduate students and researchers, assuming a basic knowledge of evolution, molecular biology, and elementary statistics, should make it possible for many investigators to incorporate refined statistical analysis of large-scale data in their own work., During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical andcomputational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present variousstatistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by workingthrough numerical examples using the computer program MEGA2 that is provided., During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided. Item Width: 9.8 in Publication Year: 2000 Format: Trade Paperback ISBN-10: 0195135857 LC Classification Number: QH390.N45 2000 Type: Textbook Intended Audience: College Audience Table Of Content: Numerical Examples1. Molecular Basis of Evolution2. Evolutionary Change of Amino Acid Sequences3. Evolutionary Change in DNA Sequences4. Synonymous and Nonsynonymous Nucleotide Substitutions5. Phylogenetic Trees6. Phylogenetic Inference: Distance Methods7. Phylogenetic Inference: Maximum Parsimony Methods8. Phylogenetic Inference: Maximum Likelihood Methods9. Accuracies and Statistical Tests of Phylogenetic Trees10. Molecular Clocks and Linearized Trees11. Ancestral Nucleotide and Amino Acid Sequences12. Genetic Polymorphism and Evolution13. Population Trees from Genetic Markers14. PerspectivesAppendicesReferencesIndex Subject: Life Sciences / Molecular Biology, Life Sciences / Genetics & Genomics Publisher: Oxford University Press, Incorporated Language: English LCCN: 99-039160 Subject Area: Science gtin13: 9780195135855

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  1. This book is a must-have for anyone studying molecular evolution! Nei and Kumar break down complex concepts clearly, making it accessible yet deeply informative. The examples and diagrams help solidify understanding, and the paperback is lightweight for easy reference. Great condition, fast shipping—highly recommend for students and researchers alike!

    Alexey K15d0