Alteraes genticas em pacientes com cancro da tiride do Vale da Caxemira by Mosin-image

Alteraes genticas em pacientes com cancro da tiride do Vale da Caxemira by Mosin

$ 57.38

Author: Mosin S. Khan, Syed Mudassar, Shariq Rashid Masoodi Type: NA Book Title: Alteraes genticas em pacientes com cancro da tiride do Vale da Ca ISBN: 9786208922009 gtin13: 9786208922009 Publication Name: NA Language: Portuguese Format: Paperback ISBN-13: 9786208922009

Description

Alteraes genticas em pacientes com cancro da tiride do Vale da Caxemira by Mosin S. Khan, Syed Mudassar, Shariq Rashid Masoodi Estimated delivery 3-12 business days Format Paperback Condition Brand New Description O carcinoma da tiróide é a neoplasia maligna endócrina mais prevalente e representa 2% de todos os cancros humanos. Analisámos o exão 15 do gene BRAF e os exões 1 e 2 dos genes RAS em sessenta (60) amostras consecutivas de tecido da tiróide (tumor e tecido normal adjacente). No geral, foram encontradas mutações no BRAF em 25% (15 de 60) dos casos, afetando o códon 600 (valina para glutamina) e restritas apenas ao cancro papilar da tiróide, mas sem qualquer mutação no RAS. Analisámos 140 amostras de sangue de pacientes com cancro da tiróide para HRAS T81C e polimorfismo RET em comparação com 170 controles sem cancro. O gene TSHR foi encontrado hipermetilado em 25% (15 de 60) dos casos, com forte associação com níveis elevados de TSH. Concluímos que tanto os eventos mutacionais quanto a superexpressão do gene BRAF estão altamente implicados na patogênese do cancro da tiróide e que a superexpressão da proteína BRAF é independente do estado mutacional do BRAF. Os polimorfismos HRAS T81C e RET aumentam moderadamente o risco de cancro da tiróide. O nosso estudo mostrou uma alta implicação da metilação do gene TSHR e sua associação significativa com a mutação BRAF V600E em tumores da tiróide, retratando uma conexão positiva entre a via TSHR e a via MAP Kinase. Details ISBN 6208922003 ISBN-13 9786208922009 Title Alteraes genticas em pacientes com cancro da tiride do Vale da Caxemira Author Mosin S. Khan, Syed Mudassar, Shariq Rashid Masoodi Format Paperback Year 2025 Pages 192 Publisher Edicoes Nosso Conhecimento GE_Item_ID:173945731; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

  1. Seller sent me the wrong book, but the book they sent sounded interesting enough for me to keep it. I still contacted the seller and communication was fast and professional. They apologized for sending me the wrong book and said I could return it for a refund. I told them that I liked the book they sent me and wanted to keep it. They were happy. Told them thank you and happy new year. People make mistakes, but the fact that this seller was quick and professional and apologized made a difference.

    Prototype074

  2. The basket is perfectly what I ordered and as listed. It came in the factory packaging and was perfect upon delivery. Thank you postal service lol. The delivery took way longer than listed though, it was listed to come in a week from purchase, but took a whole month. I had some concerns at first, but communication with the company was top notch and they were very professional and answered most of my questions satisfyingly. Just prepare for a longer wait than listed, but I got what I bought lol.

    coalmineedbb

  3. The two new out-of-print books I ordered were exactly as described and shipped promptly. I did ask the seller's support person (an AI chatbot, I think) to be sure to package the items carefully, and "he" said that he'd make that request of the shipping department. I knew this was hooey, and as I expected, the books were shipped in nothing but a padded paper mailer, no other protection. I got lucky, no damage, but don't bother making special requests of this seller.

    Olivier Marguillard

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